

Inspired by a true story, a comedy centered on a 27-year-old guy who learns of his cancer diagnosis and his subsequent struggle to beat the disease.
Acting
Gordon-Levitt's panic attack in the car — silent and devastating
Writing
Rogen's Kyle uses humor as armor, never becomes punchline
Direction
Levine finds comedy in chemo chairs without mocking patients

Director
Jonathan Levine
Trivia, insights & behind the scenes
Screenwriter Will Reiser based the script on his own spinal cancer diagnosis at 25; Seth Rogen was his actual best friend who helped him through treatment.
The title refers to Adam's survival odds, but the film quietly argues friendship is the 50/50 gamble that actually matters — and Kyle keeps betting on Adam even when the odds suck.