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What if the cure for everything was growing in your backyard—and the government wanted it dead?
Currently Airing
TMDB
84
IMDb
85
Rotten Tomatoes
100
Audience Score
91
Google
90
Watch(US)

Common Side Effects (2025)

paranoid stoner energyrotoscope fever dreamconspiracy rabbit hole

Latest Episode

Raid
7.923 min

Season 1 • Episode 10

Latest

Raid

Mar 30, 2025

Dangerous forces converge on Marshall's camp.

Overview

AnimationComedyDramaSci-Fi & Fantasy

Former high school lab partners Marshall and Frances begin to unravel a conspiracy involving big pharma and the federal government to suppress knowledge of a rare mushroom that may hold the key to curing all the world’s diseases.

Flag of USUS
Content warning
dark comedyconspiracyadult animationcomedy thrillerambiguousintrospectivegovernment conspiracymushroommiracle curepharmaceutical industry

Standout Aspects

Writing

Dialogue that weaponizes awkward silence

Direction

Bennett's eye for beauty in mundane decay

Best for:Solo: Late night when your brain wants to spiral about capitalism·Binge: Both seasons back-to-back, let the paranoia marinade·Friends: With someone who won't judge your mushroom theories
Heads up:Triggers: Medical trauma, parental death, institutional betrayal·Drug Use: Frequent mushroom use, addiction depicted with nuance
S
Joseph Bennett

Creators

Steve Hely, Joseph Bennett

First AiredFeb 2, 2025
StatusOngoing

Vibe

Pacesteady
Intensitymedium
Tonedark
Feelheavy
Seasons2·Episodes10
Adult Swim

Top Cast

Dave King

Dave King

Marshall Cuso (voice)

Emily Pendergast

Emily Pendergast

Frances Applewhite (voice)

Mike Judge

Mike Judge

Rick Kruger (voice)

Martha Kelly

Martha Kelly

Agent Harrington (voice)

Joseph Lee Anderson

Joseph Lee Anderson

Agent Copano (voice)

Ask about Common Side Effects

Opens AI chat

Deep Dive

Trivia, insights & behind the scenes

Trivia

Joseph Bennett co-directed 'Scavengers Revenge' for Love, Death + Robots—the same rotoscope obsession with biological transformation.

Cultural

The series dropped as Ozempic discourse peaked, making its pharma critique accidentally perfect timing—or terrifyingly intentional.

YouTube

Official Trailer [Adult Swim Europe]

Official Trailer [Adult Swim Europe]

Gallery(14 images)

Reviews

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